butabarbital decreases outcomes of sufentanil SL by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Monitor Carefully. Coadministration of CYP3A4 inducers may lessen sufentanil degrees and efficacy, maybe precipitating withdrawal syndrome in patients who've created Bodily dependence to sufentanil. Discontinuation of concomitantly utilised CYP3A4 inducers may raise sufentanil plasma concentration.
butabarbital will reduce the level or impact of conivaptan by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.
butabarbital will lessen the extent or influence of diazepam intranasal by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep an eye on. Sturdy or moderate CYP3A4 inducers might raise rate of diazepam elimination; hence, efficacy of diazepam may be diminished.
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butabarbital will minimize the level or effect of fostemsavir by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated.
butabarbital will lower the extent or influence of stiripentol by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Stay clear of or Use Alternate Drug. If struggling to stay away check here from coadministration of stiripentol with solid CYP3A4 inducers, boost stiripentol dose.
butabarbital will minimize the level or effect of bexarotene by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.
butabarbital will minimize the level or impact of lopinavir by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe.
butabarbital will lessen the extent or outcome of buprenorphine subdermal implant by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Keep track of Intently. Watch patients already on buprenorphine subdermal implant who call for recently-initiated treatment with CYP3A4 inducer for symptoms and indications of withdrawal.
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butabarbital will minimize the level or outcome of eplerenone by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Slight/Significance Unfamiliar.
butabarbital will reduce the level or outcome of buprenorphine, prolonged-performing injection by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Keep an eye on Intently. Individuals who transfer to buprenorphine very long-acting injection from transmucosal buprenorphine coadministered with CYP3A4 inducers must be monitored to ensure buprenorphine plasma amounts are suitable.
butabarbital will lower the extent or effect of dasatinib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.